October 17th, 2024
PICREID collaborator Dr. Tineke Cantaert, Head of the Immunology Unit at Institut Pasteur du Cambodge, was a featured speaker in the LABEX IBEID Conference “Adapting to Change: Emerging Infectious Diseases in a Shifting Climate” (October 16-18, 2024 at Institut Pasteur, Paris). Dr. Cantaert’s research focuses on human B and T cell functionality in health and disease, with the goal of unravelling the mechanisms of protective immune responses after arbovirus infection that will lead to the design of novel vaccine candidates for control of arbovirus infection and spread. Dr. Cantaert’s talk, entitled “Human immune response to dengue virus infection” presented recent work from her laboratory analyzing the immune responses of inapparent dengue infections vs. hospitalized cases, including research funded by the PICREID project. With PICREID funding, a single cell RNA sequencing pipeline was established at Institut Pasteur du Cambodge. She presented unpublished data where she showed the associations of specific T cell subsets with a protective immune response. The quantification of these T cell subsets could potentially be used as a correlate of protection. She further explained the plans on establishing assays measuring afucosylated antibodies, a feature shown before to be associated to severe dengue, at Institut Pasteur du Cambodge.
Learn more about the LABEX IBEID project: https://www.labexibeid.fr/en/
Read some of the Cantaert Lab’s recent publications: https://picreid.org/publications/
